NSAIDS (non-steroidal anti-inflammatory drugs) are usually used for pain. They include COX-2 (cyclo-oxygenase-2) inhibitors (some taken off the market due to increased risk of heart attack and stroke), ibuprofen (Advil, Motrin), naproxen (Aleve), and aspirin. They can cause gastrointestinal bleeding, leaky gut, heart and lung complications, among other things, and—remember this for later—they interfere with the inflammation process. According to Dr Joseph Pizzorno and Dr Michael Murray, NSAID use can “deteriorate the very joints that they are taken for,” because they “turn off the chemistry to repair…” Sherry A Rogers, MD, says the drugs “all steal from cartilage chemistry, fostering breakdown of protective cartilage…” This ups your risk for surgery and eventual joint replacement.